MarketGrader Developed Markets (ex-Australia) Health Care Index


Five Largest Companies
Symbol Name Grade Market Cap Country
LLY Eli Lilly and Company 66.9 ¤728,809 US
NOVO.B.DK Novo Nordisk A/S Class B 72.6 ¤215,776 DK
MRK Merck & Co., Inc. 62.0 ¤200,531 US
ISRG Intuitive Surgical, Inc. 63.4 ¤173,273 US
AMGN Amgen Inc. 62.2 ¤162,355 US

Five Smallest Companies
Symbol Name Grade Market Cap Country
SRPT Sarepta Therapeutics, Inc. 27.0 ¤1,681 US
LNTH Lantheus Holdings Inc 61.5 ¤4,944 US
SFZN.CH Siegfried Holding AG 53.1 ¤4,960 CH
HLUN.B.DK H. Lundbeck A/S Class B 69.9 ¤5,198 DK
326030.KR SK Biopharmaceuticals Co., Ltd. 71.6 ¤5,435 KR

Companies with Most Selections Among Current Components
Symbol Name Grade Times* Country
NOVO.B.DK Novo Nordisk A/S Class B 72.6 36 DK
BIIB Biogen Inc. 59.5 30 US
AMGN Amgen Inc. 62.2 29 US
ISRG Intuitive Surgical, Inc. 63.4 25 US
REGN Regeneron Pharmaceuticals, Inc. 58.3 23 US
RMD ResMed Inc. 73.0 23 US
EW Edwards Lifesciences Corporation 46.7 22 US
LLY Eli Lilly and Company 66.9 21 US
4507.JP Shionogi & Co., Ltd. 68.2 20 JP
4519.JP Chugai Pharmaceutical Co., Ltd. 61.0 19 JP
*Number of times selected at Index semi-annual reconstitutions since inception date.
Index Bio
Average Market Cap ¤53,754
Median Market Cap ¤14,231
Avg. 3 Mo. Dollar Vol. ¤327,494,773
Avg. 3 Mo. Trading Vol. 3,730,246
Last Rebalance Date 03/24/2025
Companies Replaced 16
Biggest Industry Increase Pharmaceuticals: Major
Biggest Industry Decrease Medical Specialties

Fundamental Attributes
Trailing P/E Ratio (12 Mo.) 21.8
Forward P/E Ratio (12 Mo.) 19.8
Price/Book Ratio 4.7
Avg. Revenue Chg. - 3 Yr 40.9%
Avg. Op. Income Chg. - 3 Yr. 53.6%
Avg. EPS Growth - 3 Yr. 15.9%
Avg. EPS Growth - 1 Yr. 10.7%
Avg. Operating Margin 23.6%
Avg. LT Debt to Total Capital 33.3%
Avg. Return on Equity 19.3%
Dividend Yield 0%
Index Average Grade
Developed Markets (ex-Australia) Health Care Index 61.49
Country Breakdown
United States Of America 68.0%
Japan 12.0%
Denmark 8.0%
Korea, Republic Of 4.0%
Sweden 2.0%
Finland 2.0%
Ireland 2.0%
Switzerland 2.0%
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