MarketGrader Developed Markets (ex-Australia) Health Care Index


Five Largest Companies
Symbol Name Grade Market Cap Country
LLY Eli Lilly and Company 67.5 ¤673,574 US
NOVO.B.DK Novo Nordisk A/S Class B 71.1 ¤251,481 DK
MRK Merck & Co., Inc. 62.3 ¤218,231 US
ISRG Intuitive Surgical, Inc. 63.7 ¤170,692 US
AMGN Amgen Inc. 61.9 ¤158,128 US

Five Smallest Companies
Symbol Name Grade Market Cap Country
SRPT Sarepta Therapeutics, Inc. 50.3 ¤1,976 US
LNTH Lantheus Holdings Inc 71.5 ¤3,958 US
SFZN.CH Siegfried Holding AG 52.7 ¤4,674 CH
326030.KR SK Biopharmaceuticals Co., Ltd. 79.3 ¤5,572 KR
HLUN.B.DK H. Lundbeck A/S Class B 69.2 ¤6,151 DK

Companies with Most Selections Among Current Components
Symbol Name Grade Times* Country
NOVO.B.DK Novo Nordisk A/S Class B 71.1 36 DK
BIIB Biogen Inc. 59.8 30 US
AMGN Amgen Inc. 61.9 29 US
ISRG Intuitive Surgical, Inc. 63.7 25 US
REGN Regeneron Pharmaceuticals, Inc. 62.9 23 US
RMD ResMed Inc. 73.0 23 US
EW Edwards Lifesciences Corporation 42.7 22 US
LLY Eli Lilly and Company 67.5 21 US
4507.JP Shionogi & Co., Ltd. 66.4 20 JP
4519.JP Chugai Pharmaceutical Co., Ltd. 62.4 19 JP
*Number of times selected at Index semi-annual reconstitutions since inception date.
Index Bio
Average Market Cap ¤54,051
Median Market Cap ¤15,026
Avg. 3 Mo. Dollar Vol. ¤321,708,086
Avg. 3 Mo. Trading Vol. 3,564,102
Last Rebalance Date 03/24/2025
Companies Replaced 16
Biggest Industry Increase Pharmaceuticals: Major
Biggest Industry Decrease Medical Specialties

Fundamental Attributes
Trailing P/E Ratio (12 Mo.) 24.0
Forward P/E Ratio (12 Mo.) 19.0
Price/Book Ratio 4.9
Avg. Revenue Chg. - 3 Yr 39.1%
Avg. Op. Income Chg. - 3 Yr. 53.6%
Avg. EPS Growth - 3 Yr. 16.0%
Avg. EPS Growth - 1 Yr. 11.5%
Avg. Operating Margin 23.8%
Avg. LT Debt to Total Capital 34.2%
Avg. Return on Equity 19.2%
Dividend Yield 0%
Index Average Grade
Developed Markets (ex-Australia) Health Care Index 62.33
Country Breakdown
United States Of America 68.0%
Japan 12.0%
Denmark 8.0%
Korea, Republic Of 4.0%
Sweden 2.0%
Finland 2.0%
Ireland 2.0%
Switzerland 2.0%
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