MarketGrader Developed Markets (ex-Australia) Health Care Index


Five Largest Companies
Symbol Name Grade Market Cap Country
LLY Eli Lilly and Company 73.2 ¤796,273 US
NOVO.B.DK Novo Nordisk A/S Class B 77.1 ¤285,495 DK
MRK Merck & Co., Inc. 72.5 ¤196,278 US
ISRG Intuitive Surgical, Inc. 62.1 ¤172,954 US
AMGN Amgen Inc. 54.2 ¤149,085 US

Five Smallest Companies
Symbol Name Grade Market Cap Country
HLUN.B.DK H. Lundbeck A/S Class B 61.1 ¤4,322 DK
SFZN.CH Siegfried Holding AG 58.0 ¤4,754 CH
ALK.B.DK ALK-abello A/S Class B 70.8 ¤5,023 DK
SRPT Sarepta Therapeutics, Inc. 63.2 ¤5,219 US
326030.KR SK Biopharmaceuticals Co., Ltd. 73.8 ¤5,786 KR

Companies with Most Selections Among Current Components
Symbol Name Grade Times* Country
NOVO.B.DK Novo Nordisk A/S Class B 77.1 36 DK
BIIB Biogen Inc. 57.1 30 US
AMGN Amgen Inc. 54.2 29 US
ISRG Intuitive Surgical, Inc. 62.1 25 US
REGN Regeneron Pharmaceuticals, Inc. 62.3 23 US
RMD ResMed Inc. 69.1 23 US
EW Edwards Lifesciences Corporation 47.6 22 US
LLY Eli Lilly and Company 73.2 21 US
4507.JP Shionogi & Co., Ltd. 67.5 20 JP
4519.JP Chugai Pharmaceutical Co., Ltd. 68.5 19 JP
*Number of times selected at Index semi-annual reconstitutions since inception date.
Index Bio
Average Market Cap ¤54,550
Median Market Cap ¤12,916
Avg. 3 Mo. Dollar Vol. ¤328,312,601
Avg. 3 Mo. Trading Vol. 3,424,709
Last Rebalance Date 03/24/2025
Companies Replaced 16
Biggest Industry Increase Pharmaceuticals: Major
Biggest Industry Decrease Medical Specialties

Fundamental Attributes
Trailing P/E Ratio (12 Mo.) 23.2
Forward P/E Ratio (12 Mo.) 19.0
Price/Book Ratio 4.3
Avg. Revenue Chg. - 3 Yr 41.4%
Avg. Op. Income Chg. - 3 Yr. 38.4%
Avg. EPS Growth - 3 Yr. 12.2%
Avg. EPS Growth - 1 Yr. 12.2%
Avg. Operating Margin 22.4%
Avg. LT Debt to Total Capital 33.3%
Avg. Return on Equity 20.6%
Dividend Yield 0%
Index Average Grade
Developed Markets (ex-Australia) Health Care Index 62.41
Country Breakdown
United States Of America 68.0%
Japan 12.0%
Denmark 8.0%
Korea, Republic Of 4.0%
Sweden 2.0%
Finland 2.0%
Ireland 2.0%
Switzerland 2.0%
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