MarketGrader Developed Markets (ex-Australia) Health Care Index


Five Largest Companies
Symbol Name Grade Market Cap Country
LLY Eli Lilly and Company 78.5 ¤929,545 US
JNJ Johnson & Johnson 51.9 ¤540,710 US
AZN.GB AstraZeneca PLC 60.7 ¤285,912 GB
MRK Merck & Co., Inc. 63.7 ¤280,473 US
NOVO.B.DK Novo Nordisk A/S Class B 69.6 ¤204,189 DK

Five Smallest Companies
Symbol Name Grade Market Cap Country
YPSN.CH Ypsomed Holding AG 74.3 ¤4,884 CH
326030.KR SK Biopharmaceuticals Co., Ltd. 69.2 ¤5,337 KR
HALO Halozyme Therapeutics, Inc. 62.3 ¤7,861 US
4151.JP Kyowa Kirin Co., Ltd. 66.2 ¤7,979 JP
ALK.B.DK ALK-abello A/S Class B 74.2 ¤8,981 DK

Companies with Most Selections Among Current Components
Symbol Name Grade Times* Country
NOVO.B.DK Novo Nordisk A/S Class B 69.6 38 DK
AMGN Amgen Inc. 62.2 31 US
ISRG Intuitive Surgical, Inc. 71.9 27 US
RMD ResMed Inc. 67.4 25 US
JNJ Johnson & Johnson 51.9 24 US
LLY Eli Lilly and Company 78.5 23 US
4507.JP Shionogi & Co., Ltd. 69.7 22 JP
BMY Bristol-Myers Squibb Company 61.9 22 US
4519.JP Chugai Pharmaceutical Co., Ltd. 65.6 21 JP
7741.JP HOYA CORPORATION 68.5 21 JP
*Number of times selected at Index semi-annual reconstitutions since inception date.
Index Bio
Average Market Cap ¤80,725
Median Market Cap ¤25,172
Avg. 3 Mo. Dollar Vol. ¤350,768,870
Avg. 3 Mo. Trading Vol. 2,630,343
Last Rebalance Date 03/23/2026
Companies Replaced 11
Biggest Industry Increase Medical Specialties
Biggest Industry Decrease Pharmaceuticals: Major

Fundamental Attributes
Trailing P/E Ratio (12 Mo.) 25.9
Forward P/E Ratio (12 Mo.) 18.7
Price/Book Ratio 5.9
Avg. Revenue Chg. - 3 Yr 42.9%
Avg. Op. Income Chg. - 3 Yr. 83.5%
Avg. EPS Growth - 3 Yr. 22.2%
Avg. EPS Growth - 1 Yr. 16.7%
Avg. Operating Margin 26.7%
Avg. LT Debt to Total Capital 18.5%
Avg. Return on Equity 22.9%
Dividend Yield 0.4%
Index Average Grade
Developed Markets (ex-Australia) Health Care Index 67.14
Country Breakdown
United States Of America 58.0%
Japan 14.0%
Korea, Republic Of 6.0%
Denmark 4.0%
United Kingdom 4.0%
Israel 2.0%
Finland 2.0%
France 2.0%
Belgium 2.0%
Switzerland 2.0%
Netherlands 2.0%
New Zealand 2.0%
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