MarketGrader Developed Markets (ex-Australia) Health Care Index


Five Largest Companies
Symbol Name Grade Market Cap Country
LLY Eli Lilly and Company 74.4 ¤1,001,823 US
JNJ Johnson & Johnson 64.9 ¤491,256 US
AZN.GB AstraZeneca PLC 68.7 ¤280,785 GB
MRK Merck & Co., Inc. 68.0 ¤242,642 US
ABT Abbott Laboratories 59.6 ¤222,767 US

Five Smallest Companies
Symbol Name Grade Market Cap Country
YPSN.CH Ypsomed Holding AG 73.7 ¤5,552 CH
326030.KR SK Biopharmaceuticals Co., Ltd. 77.8 ¤6,712 KR
HLUN.B.DK H. Lundbeck A/S Class B 70.2 ¤6,755 DK
ALK.B.DK ALK-abello A/S Class B 76.3 ¤7,772 DK
CORT Corcept Therapeutics Incorporated. 40.6 ¤8,130 US

Companies with Most Selections Among Current Components
Symbol Name Grade Times* Country
NOVO.B.DK Novo Nordisk A/S Class B 62.2 37 DK
BIIB Biogen Inc. 60.9 31 US
AMGN Amgen Inc. 68.1 30 US
ISRG Intuitive Surgical, Inc. 71.0 26 US
REGN Regeneron Pharmaceuticals, Inc. 64.2 24 US
RMD ResMed Inc. 69.4 24 US
JNJ Johnson & Johnson 64.9 23 US
LLY Eli Lilly and Company 74.4 22 US
4507.JP Shionogi & Co., Ltd. 62.2 21 JP
BMY Bristol-Myers Squibb Company 64.1 21 US
*Number of times selected at Index semi-annual reconstitutions since inception date.
Index Bio
Average Market Cap ¤84,350
Median Market Cap ¤21,275
Avg. 3 Mo. Dollar Vol. ¤365,695,505
Avg. 3 Mo. Trading Vol. 3,679,974
Last Rebalance Date 09/22/2025
Companies Replaced 14
Biggest Industry Increase Biotechnology
Biggest Industry Decrease Medical/Nursing Services

Fundamental Attributes
Trailing P/E Ratio (12 Mo.) 25.6
Forward P/E Ratio (12 Mo.) 20.5
Price/Book Ratio 5.2
Avg. Revenue Chg. - 3 Yr 39.4%
Avg. Op. Income Chg. - 3 Yr. 76.8%
Avg. EPS Growth - 3 Yr. 22.2%
Avg. EPS Growth - 1 Yr. 15.6%
Avg. Operating Margin 25.8%
Avg. LT Debt to Total Capital 20.2%
Avg. Return on Equity 20.0%
Dividend Yield 0.3%
Index Average Grade
Developed Markets (ex-Australia) Health Care Index 64.86
Country Breakdown
United States Of America 62.0%
Japan 12.0%
Denmark 8.0%
Korea, Republic Of 6.0%
Netherlands 2.0%
Sweden 2.0%
Finland 2.0%
United Kingdom 2.0%
Belgium 2.0%
Switzerland 2.0%
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