MarketGrader Developed Markets (ex-Australia) Health Care Index


Five Largest Companies
Symbol Name Grade Market Cap Country
LLY Eli Lilly and Company 72.0 ¤964,130 US
JNJ Johnson & Johnson 63.4 ¤586,738 US
AZN.GB AstraZeneca PLC 65.5 ¤316,072 GB
MRK Merck & Co., Inc. 63.3 ¤294,956 US
AMGN Amgen Inc. 65.0 ¤204,485 US

Five Smallest Companies
Symbol Name Grade Market Cap Country
CORT Corcept Therapeutics Incorporated. 40.4 ¤3,806 US
YPSN.CH Ypsomed Holding AG 75.0 ¤4,758 CH
HLUN.B.DK H. Lundbeck A/S Class B 58.7 ¤6,015 DK
326030.KR SK Biopharmaceuticals Co., Ltd. 65.5 ¤6,430 KR
ALK.B.DK ALK-abello A/S Class B 72.8 ¤7,350 DK

Companies with Most Selections Among Current Components
Symbol Name Grade Times* Country
NOVO.B.DK Novo Nordisk A/S Class B 59.4 37 DK
BIIB Biogen Inc. 49.5 31 US
AMGN Amgen Inc. 65.0 30 US
ISRG Intuitive Surgical, Inc. 66.0 26 US
REGN Regeneron Pharmaceuticals, Inc. 55.6 24 US
RMD ResMed Inc. 71.3 24 US
JNJ Johnson & Johnson 63.4 23 US
LLY Eli Lilly and Company 72.0 22 US
4507.JP Shionogi & Co., Ltd. 67.2 21 JP
BMY Bristol-Myers Squibb Company 62.3 21 US
*Number of times selected at Index semi-annual reconstitutions since inception date.
Index Bio
Average Market Cap ¤86,775
Median Market Cap ¤20,842
Avg. 3 Mo. Dollar Vol. ¤381,242,409
Avg. 3 Mo. Trading Vol. 3,366,519
Last Rebalance Date 09/22/2025
Companies Replaced 14
Biggest Industry Increase Biotechnology
Biggest Industry Decrease Medical/Nursing Services

Fundamental Attributes
Trailing P/E Ratio (12 Mo.) 24.6
Forward P/E Ratio (12 Mo.) 21.1
Price/Book Ratio 5.5
Avg. Revenue Chg. - 3 Yr 41.0%
Avg. Op. Income Chg. - 3 Yr. 56.8%
Avg. EPS Growth - 3 Yr. 17.9%
Avg. EPS Growth - 1 Yr. 14.9%
Avg. Operating Margin 26.1%
Avg. LT Debt to Total Capital 21.3%
Avg. Return on Equity 19.7%
Dividend Yield 0.3%
Index Average Grade
Developed Markets (ex-Australia) Health Care Index 64.25
Country Breakdown
United States Of America 62.0%
Japan 12.0%
Denmark 8.0%
Korea, Republic Of 6.0%
Netherlands 2.0%
Sweden 2.0%
Finland 2.0%
United Kingdom 2.0%
Belgium 2.0%
Switzerland 2.0%
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