MarketGrader Developed Markets (ex-Australia) Health Care Index


Five Largest Companies
Symbol Name Grade Market Cap Country
LLY Eli Lilly and Company 66.5 ¤696,178 US
NOVO.B.DK Novo Nordisk A/S Class B 70.7 ¤297,522 DK
ISRG Intuitive Surgical, Inc. 66.5 ¤192,295 US
MRK Merck & Co., Inc. 72.4 ¤190,763 US
BSX Boston Scientific Corporation 59.6 ¤152,176 US

Five Smallest Companies
Symbol Name Grade Market Cap Country
SRPT Sarepta Therapeutics, Inc. 26.7 ¤3,565 US
HLUN.B.DK H. Lundbeck A/S Class B 61.1 ¤4,511 DK
326030.KR SK Biopharmaceuticals Co., Ltd. 75.0 ¤5,072 KR
SFZN.CH Siegfried Holding AG 52.7 ¤5,291 CH
ALK.B.DK ALK-abello A/S Class B 73.8 ¤5,471 DK

Companies with Most Selections Among Current Components
Symbol Name Grade Times* Country
NOVO.B.DK Novo Nordisk A/S Class B 70.7 36 DK
BIIB Biogen Inc. 52.4 30 US
AMGN Amgen Inc. 54.2 29 US
ISRG Intuitive Surgical, Inc. 66.5 25 US
REGN Regeneron Pharmaceuticals, Inc. 57.8 23 US
RMD ResMed Inc. 73.0 23 US
EW Edwards Lifesciences Corporation 53.5 22 US
LLY Eli Lilly and Company 66.5 21 US
4507.JP Shionogi & Co., Ltd. 66.1 20 JP
4519.JP Chugai Pharmaceutical Co., Ltd. 66.2 19 JP
*Number of times selected at Index semi-annual reconstitutions since inception date.
Index Bio
Average Market Cap ¤54,044
Median Market Cap ¤13,824
Avg. 3 Mo. Dollar Vol. ¤339,912,113
Avg. 3 Mo. Trading Vol. 3,724,825
Last Rebalance Date 03/24/2025
Companies Replaced 16
Biggest Industry Increase Pharmaceuticals: Major
Biggest Industry Decrease Medical Specialties

Fundamental Attributes
Trailing P/E Ratio (12 Mo.) 24.0
Forward P/E Ratio (12 Mo.) 18.1
Price/Book Ratio 4.5
Avg. Revenue Chg. - 3 Yr 42.5%
Avg. Op. Income Chg. - 3 Yr. 38.4%
Avg. EPS Growth - 3 Yr. 15.3%
Avg. EPS Growth - 1 Yr. 12.0%
Avg. Operating Margin 21.8%
Avg. LT Debt to Total Capital 33.3%
Avg. Return on Equity 20.6%
Dividend Yield 0%
Index Average Grade
Developed Markets (ex-Australia) Health Care Index 60.81
Country Breakdown
United States Of America 68.0%
Japan 12.0%
Denmark 8.0%
Korea, Republic Of 4.0%
Sweden 2.0%
Finland 2.0%
Ireland 2.0%
Switzerland 2.0%
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