MarketGrader Developed Markets (ex-Australia) Health Care Index


Five Largest Companies
Symbol Name Grade Market Cap Country
LLY Eli Lilly and Company 76.4 ¤1,161,314 US
JNJ Johnson & Johnson 54.7 ¤658,240 US
MRK Merck & Co., Inc. 40.1 ¤385,989 US
AZN.GB AstraZeneca PLC 63.6 ¤264,033 GB
AMGN Amgen Inc. 67.8 ¤239,089 US

Five Smallest Companies
Symbol Name Grade Market Cap Country
326030.KR SK Biopharmaceuticals Co., Ltd. 87.0 ¤4,784 KR
YPSN.CH Ypsomed Holding AG 68.9 ¤6,159 CH
ALK.B.DK ALK-abello A/S Class B 69.5 ¤7,235 DK
4151.JP Kyowa Kirin Co., Ltd. 65.3 ¤8,438 JP
PODD Insulet Corporation 74.2 ¤9,921 US

Companies with Most Selections Among Current Components
Symbol Name Grade Times* Country
NOVO.B.DK Novo Nordisk A/S Class B 67.0 38 DK
AMGN Amgen Inc. 67.8 31 US
ISRG Intuitive Surgical, Inc. 67.2 27 US
RMD ResMed Inc. 65.3 25 US
JNJ Johnson & Johnson 54.7 24 US
LLY Eli Lilly and Company 76.4 23 US
4507.JP Shionogi & Co., Ltd. 71.9 22 JP
BMY Bristol-Myers Squibb Company 67.6 22 US
4519.JP Chugai Pharmaceutical Co., Ltd. 65.4 21 JP
7741.JP HOYA CORPORATION 76.3 21 JP
*Number of times selected at Index semi-annual reconstitutions since inception date.
Index Bio
Average Market Cap ¤91,949
Median Market Cap ¤31,938
Avg. 3 Mo. Dollar Vol. ¤384,074,991
Avg. 3 Mo. Trading Vol. 2,807,441
Last Rebalance Date 03/23/2026
Companies Replaced 11
Biggest Industry Increase Medical Specialties
Biggest Industry Decrease Pharmaceuticals: Major

Fundamental Attributes
Trailing P/E Ratio (12 Mo.) 24.9
Forward P/E Ratio (12 Mo.) 20.0
Price/Book Ratio 6.5
Avg. Revenue Chg. - 3 Yr 45.0%
Avg. Op. Income Chg. - 3 Yr. 87.2%
Avg. EPS Growth - 3 Yr. 24.1%
Avg. EPS Growth - 1 Yr. 16.4%
Avg. Operating Margin 26.7%
Avg. LT Debt to Total Capital 23.5%
Avg. Return on Equity 23.5%
Dividend Yield 0.5%
Index Average Grade
Developed Markets (ex-Australia) Health Care Index 67.86
Country Breakdown
United States Of America 58.0%
Japan 14.0%
Korea, Republic Of 6.0%
Denmark 4.0%
United Kingdom 4.0%
Israel 2.0%
Finland 2.0%
France 2.0%
Belgium 2.0%
Switzerland 2.0%
Netherlands 2.0%
New Zealand 2.0%
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